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When Is Genetic Screening Recommended During IVF and Who May Need It?







“IVF treatment பண்ற எல்லாருக்கும் genetic screening தேவையா? அல்லது சில specific conditions இருந்தால் மட்டும் recommend பண்ணுவாங்களா?”

Genetic screening is not automatically recommended for every person undergoing IVF. It may be considered when a couple’s age, family history, previous pregnancy history, known genetic conditions, chromosome findings, or specific fertility circumstances indicate that additional genetic information could be useful before embryo transfer.

At Sumathi Hospital, Madurai, couples considering Genetic Screening in Madurai are evaluated individually to understand whether genetic testing is relevant to their particular IVF journey.

When Is Genetic Screening Recommended During IVF?

The recommendation usually begins with a specific reason, rather than simply because someone is undergoing IVF.

A fertility doctor may discuss genetic testing when there is a known risk of passing on a particular inherited condition, when a chromosome related issue has already been identified, or when certain aspects of a couple’s reproductive history warrant further evaluation.

The type of testing recommended will depend on what doctors are specifically looking for.

Here are some situations where genetic screening or testing may be discussed.

1. When There Is a Known Genetic Condition in the Family

If a particular inherited condition runs in either partner’s family, genetic evaluation may be considered before or during IVF.

This becomes especially relevant when one or both partners are known to carry a genetic variant associated with a specific inherited disorder.

In such situations, testing may help doctors assess embryos for that particular condition before deciding on embryo transfer.

The family history therefore gives our Fertility Specialist in Madurai an important starting point for deciding whether further genetic evaluation may be useful.

2. When One or Both Partners Are Known Carriers

Sometimes people are healthy themselves but carry a genetic variant that could potentially be passed to their children.

Carrier screening performed before fertility treatment may identify some of these situations.

If both partners carry variants associated with the same recessive genetic condition, or if a relevant inherited condition is identified through genetic evaluation, the fertility team may discuss whether embryo testing has a role in their IVF Treatment in Madurai.

The recommendation depends on the particular condition and the couple’s genetic results.

3. When a Chromosome Rearrangement Has Been Identified

Genetic testing may also be considered when one partner has a known structural chromosome rearrangement, such as a balanced translocation.

A person carrying such a rearrangement may be healthy, but it can affect how chromosome material is passed to an embryo.  

When this has already been identified through chromosome testing, the fertility team may discuss specialised embryo testing as part of IVF planning.

4. When Maternal Age Becomes an Important Consideration

Age can also become part of the genetic screening discussion.

As maternal age increases, the chance of chromosome number differences in eggs and embryos generally increases. For some patients undergoing IVF at an older reproductive age, the fertility team may therefore discuss whether chromosome screening of embryos could provide useful additional information.

However, age alone does not mean every patient requires genetic screening. The decision should consider the complete fertility situation.

At our IVF Hospital in Madurai, we assess age together with fertility history and other clinical findings before discussing additional testing.

5. When There Is a History of Recurrent Pregnancy Loss

When a woman has experienced repeated pregnancy losses, doctors may investigate several possible contributing factors.

In some cases, chromosome testing of the partners or other genetic evaluation may identify a reason to discuss genetic testing during IVF.

This does not mean that every recurrent pregnancy loss is caused by a genetic problem. Instead, the previous pregnancy history helps determine whether genetic investigation is relevant to that particular couple.

6. When a Previous Pregnancy Had a Genetic or Chromosomal Condition

A previous pregnancy affected by a diagnosed genetic or chromosomal condition can also be an important reason to seek genetic counselling before another pregnancy.

The exact diagnosis matters.

Doctors can review previous reports and determine whether there is a known recurrence risk and whether a specific type of genetic testing could be considered during IVF.

This is why bringing previous genetic reports, pregnancy records, and test results to the consultation can be useful.

What Happens If Genetic Screening Is Recommended?

The next step is not simply “do a genetic test.”

Our fertility team first explains why the test is being recommended and what it is designed to look for.

Depending on the reason, different forms of preimplantation genetic testing may be considered. For example, one type may assess chromosome numbers, while another may look for a specific inherited genetic condition.

When embryo testing is part of IVF, embryos are developed in the laboratory and a small number of cells may be collected from an embryo for analysis. The results can then contribute to embryo transfer planning.

At our Fertility Clinic in Madurai, we explain the purpose and process of testing according to each patient's individual fertility plan.

Who Should Discuss Genetic Screening With Their Fertility Team?

You may consider asking about genetic screening if you:

  • Have a known inherited condition in your family

  • Know that you or your partner carries a genetic condition

  • Have a diagnosed chromosome rearrangement

  • Have experienced recurrent pregnancy loss and are undergoing evaluation

  • Had a previous pregnancy affected by a diagnosed genetic or chromosomal condition

  • Are undergoing IVF and have been advised to discuss embryo chromosome testing based on your individual clinical circumstances

Having one of these factors does not automatically mean a particular genetic test will be recommended. It means there may be a reason to have a more detailed genetic and fertility evaluation.

The Recommendation Should Match the Reason

The simplest answer to “When is genetic screening recommended during IVF?” is: when there is a specific genetic, chromosomal, reproductive, or clinical reason for the information it can provide.

And who may need it? Couples with known inherited conditions, carrier findings, chromosome rearrangements, certain previous pregnancy histories, recurrent pregnancy loss under evaluation, or other relevant IVF circumstances may be advised to discuss genetic testing.

At Sumathi Hospital, Madurai, we review each couple’s medical, fertility, family, and relevant genetic history before recommending additional investigations. The goal is to ensure that when genetic screening is considered, patients understand why it is being recommended, what it can assess, and how the information may contribute to their IVF plan.


For more details:

Call: 73588 00889
Visit: Sumathi Hospital, Madurai






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